Multicentric Castleman's disease in a Ghanaian adult

Ghana Med J. 2013 Jun;47(2):92-5.

Abstract

Castleman's disease is a rare cause of lymphoid hyperplasia that may result in localized symptoms or an aggressive, multisystem disorder that can mimic other diseases like lymphoma or tuberculosis. We describe a case of a 55-year-old Ghanaian male who was successfully diagnosed and managed for multicentric Castleman's disease with combination chemotherapy.

Keywords: Plasma cell; Rituximab; chemotherapy; lymphadenopathy; multicentric Castleman's disease.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Monoclonal, Murine-Derived / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Biopsy
  • Castleman Disease / diagnosis
  • Castleman Disease / drug therapy*
  • Castleman Disease / pathology*
  • Cyclophosphamide / administration & dosage
  • Humans
  • Immunohistochemistry
  • Male
  • Middle Aged
  • Prednisolone / administration & dosage
  • Rituximab
  • Vincristine / administration & dosage

Substances

  • Antibodies, Monoclonal, Murine-Derived
  • Rituximab
  • Vincristine
  • Cyclophosphamide
  • Prednisolone