Mild mitochondrial uncoupling prevents premature senescence in human dermal fibroblasts

J Invest Dermatol. 2014 Feb;134(2):540-543. doi: 10.1038/jid.2013.352. Epub 2013 Aug 20.

Authors

Si Young Cho¹, Dae-Bang Seo¹, Wan Gi Kim¹, Sang-Jun Lee²

Affiliations

¹ Health Science Research Institute, R&D Center, AmorePacific Corporation, Gyeonggi-do, Korea.
² Health Science Research Institute, R&D Center, AmorePacific Corporation, Gyeonggi-do, Korea. Electronic address: leesjun@amorepacific.com.

PMID: 23962811
DOI: 10.1038/jid.2013.352

No abstract available

Publication types

Letter

MeSH terms

Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone / pharmacology*
Cellular Senescence / drug effects*
Cellular Senescence / physiology
Dermis / cytology
Fibroblasts / cytology
Fibroblasts / drug effects*
Fibroblasts / metabolism
Humans
Mitochondria / drug effects*
Mitochondria / metabolism
Proton Ionophores / pharmacology
Skin Aging / drug effects*
Skin Aging / physiology

Substances

Proton Ionophores
Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone