Abstract
Gold nanoparticles coated with fluorinated ligands (F-MPCs) present features suitable for (19)F MRI as observed from phantom experiments. Cellular uptake, by HeLa cells, and toxicity of fluorescent dye-decorated F-MPCs are presented together with their ability to bind hydrophobic molecules allowing for a potential combination of targeting, delivery and imaging features.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Fluorine Compounds / chemistry*
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Fluorine Compounds / metabolism
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Fluorine Compounds / toxicity
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Gold / chemistry*
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Gold / metabolism
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Gold / toxicity
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Halogenation
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HeLa Cells
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Humans
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Ligands
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Magnetic Resonance Imaging
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Models, Molecular
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Nanoparticles / chemistry*
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Nanoparticles / metabolism
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Nanoparticles / toxicity
Substances
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Fluorine Compounds
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Ligands
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Gold