Catalytic enantioselective Amadori-Heyns rearrangement of racemic α-hydroxy ketones with arylamines: synthesis of optically active α-arylamino ketones

Chem Commun (Camb). 2013 Oct 9;49(78):8812-4. doi: 10.1039/c3cc45278f.

Abstract

A novel synthesis of optically active α-arylamino ketones through an organocatalytic enantioselective Amadori-Heyns rearrangement is described.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amines / chemical synthesis*
  • Amines / chemistry
  • Catalysis
  • Cinchona Alkaloids / chemistry
  • Hydrocarbons, Aromatic / chemical synthesis*
  • Hydrocarbons, Aromatic / chemistry
  • Ketones / chemical synthesis*
  • Ketones / chemistry
  • Stereoisomerism

Substances

  • Amines
  • Cinchona Alkaloids
  • Hydrocarbons, Aromatic
  • Ketones