Outcome of total knee arthroplasty in hemophilic arthropathy

J Arthroplasty. 2014 Apr;29(4):749-52. doi: 10.1016/j.arth.2013.07.014. Epub 2013 Aug 17.

Abstract

The clinical histories of 45 consecutively performed TKAs in 32 patients with hereditary bleeding disorders were reviewed retrospectively. The mean follow up was 88.7 (range, 24-232) months. The cumulative probability of infection free-survival was 87.8% after 180 months. When removal of component was defined as endpoint, the survival probability was 86.4% after 180 months. In regression analysis no significant independent risk factors for infection or aseptic loosening were identified. The HSS score improved significantly from 45 to 85 points. Hemophilic patients can be considered to be at high risk for prosthetic failure, our study has demonstrated favorable functional results of total knee arthroplasty in hemophilic patients.

Keywords: arthroplasty; haemophilia; hemophilic arthropathy; knee; outcome.

MeSH terms

  • Adult
  • Arthroplasty, Replacement, Knee / adverse effects*
  • Blood Coagulation Disorders, Inherited / complications*
  • Blood Coagulation Disorders, Inherited / therapy
  • Humans
  • Joint Diseases / etiology
  • Joint Diseases / surgery*
  • Knee Joint / surgery*
  • Knee Prosthesis / adverse effects
  • Male
  • Middle Aged
  • Prosthesis Failure / etiology
  • Prosthesis-Related Infections / etiology
  • Reoperation
  • Retrospective Studies
  • Treatment Outcome
  • Young Adult