Clinical study report on milk production in the offspring of a somatic cell cloned Holstein cow

J Reprod Dev. 2013 Dec 17;59(6):595-8. doi: 10.1262/jrd.2013-025. Epub 2013 Aug 17.

Abstract

This study examined two female offspring of a somatic cell cloned Holstein cow that had reproduction problems and milk production performance issues. The two offspring heifers, which showed healthy appearances and normal reproductive characteristics, calved on two separate occasions. The mean milk yields of the heifers in the first lactation period were 9,037 kg and 7,228 kg. The relative mean milk yields of these cows were 111.2% and 88.9%, respectively, when compared with that of the control group. No particular clinical abnormalities were revealed in milk yields and milk composition rate [e.g., fat, protein and solids-not-fat (SNF)], and reproductive characteristics of the offspring of the somatic cell cloned Holstein cow suggested that the cloned offspring had normal milk production.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Inbred Strains
  • Cattle / genetics*
  • Cattle / growth & development
  • Cattle / physiology
  • Cattle Diseases / etiology
  • Cattle Diseases / physiopathology
  • Cattle Diseases / therapy*
  • Cloning, Organism / adverse effects
  • Cloning, Organism / veterinary*
  • Crosses, Genetic
  • Dairying
  • Embryo Culture Techniques / veterinary
  • Embryo Transfer / veterinary
  • Female
  • Fertility
  • Infertility, Female / etiology
  • Infertility, Female / physiopathology
  • Infertility, Female / therapy
  • Infertility, Female / veterinary*
  • Insemination, Artificial / veterinary
  • Japan
  • Lactation / metabolism
  • Mammary Glands, Animal / growth & development
  • Mammary Glands, Animal / metabolism*
  • Mammary Glands, Animal / physiology
  • Mammary Glands, Animal / physiopathology
  • Milk / chemistry
  • Milk / metabolism*
  • Nuclear Transfer Techniques / adverse effects
  • Nuclear Transfer Techniques / veterinary*
  • Pregnancy