Preoperative aspiration culture for preoperative diagnosis of infection in total hip or knee arthroplasty

Xinhua Qu; Zanjing Zhai; Chuanlong Wu; Fangchun Jin; Haowei Li; Lei Wang; Guangwang Liu; Xuqiang Liu; Wengang Wang; Huiwu Li; Xiaoyu Zhang; Zhenan Zhu; Kerong Dai

doi:10.1128/JCM.01467-13

Preoperative aspiration culture for preoperative diagnosis of infection in total hip or knee arthroplasty

J Clin Microbiol. 2013 Nov;51(11):3830-4. doi: 10.1128/JCM.01467-13. Epub 2013 Aug 14.

Authors

Xinhua Qu¹, Zanjing Zhai, Chuanlong Wu, Fangchun Jin, Haowei Li, Lei Wang, Guangwang Liu, Xuqiang Liu, Wengang Wang, Huiwu Li, Xiaoyu Zhang, Zhenan Zhu, Kerong Dai

Affiliation

¹ Department of Orthopedics, Shanghai Key Laboratory of Orthopedic Implant, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

Abstract

This meta-analysis evaluated preoperative aspiration culture for diagnosing prosthetic joint infection (PJI) in total hip arthroplasty (THA) and total knee arthroplasty (TKA). The pooled sensitivity and specificity were 0.72 (95% confidence interval, 0.65 to 0.78) and 0.95 (0.93 to 0.97), respectively. Subgroup analyses revealed nonsignificant worse diagnostic performance for THA than for TKA (sensitivity, 0.70 versus 0.78; specificity, 0.94 versus 0.96). Preoperative aspiration culture has moderate to high sensitivity and very high specificity for diagnosing PJI.

Publication types

Evaluation Study
Meta-Analysis
Research Support, Non-U.S. Gov't

MeSH terms

Aged
Arthroplasty, Replacement, Hip / adverse effects
Arthroplasty, Replacement, Knee / adverse effects
Female
Humans
Male
Microbiological Techniques / methods*
Preoperative Care / methods*
Prosthesis-Related Infections / diagnosis*
Sensitivity and Specificity
Specimen Handling / methods*