Evidence for continuing cross-species transmission of SIVsmm to humans: characterization of a new HIV-2 lineage in rural Côte d'Ivoire

AIDS. 2013 Sep 24;27(15):2488-91. doi: 10.1097/01.aids.0000432443.22684.50.

Abstract

HIV types 1 and 2 (HIV-1 and HIV-2) are the result of multiple cross-species transmissions of their simian counterparts (SIVs) to humans. We studied whether new SIVs lineages have been transmitted to humans in rural Côte d'Ivoire and identified a novel HIV-2 variant (HIV-2-07IC-TNP03) not related to any of the previously defined HIV-2 groups. This finding shows that sooty mangabey viruses continue to be transmitted to humans, causing new zoonotic outbreaks.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cercocebus atys
  • Cote d'Ivoire / epidemiology
  • HIV Infections / genetics*
  • HIV-2 / classification
  • HIV-2 / genetics*
  • Humans
  • Molecular Sequence Data
  • Simian Immunodeficiency Virus / genetics*
  • Zoonoses / genetics

Associated data

  • GENBANK/KC693496
  • GENBANK/KC693497
  • GENBANK/KC693498
  • GENBANK/KC693499
  • GENBANK/KC693500
  • GENBANK/KC693501
  • GENBANK/KC693502
  • GENBANK/KC693503
  • GENBANK/KC693504
  • GENBANK/KC693505