Hypocalcemia in a paediatric case: from the clinical features to diagnosis

J Pediatr Endocrinol Metab. 2014 Jan;27(1-2):139-42. doi: 10.1515/jpem-2013-0149.

Abstract

Pseudohypoparathyroidism refers to end-organ resistance that primarily impairs the renal actions of parathyroid hormone (PTH), a key regulator of calcium homeostasis. Its diagnosis is complex because of the multiple variants of this entity, and more so because intravenous PTH is not available for the Ellsworth-Howard test. We report a symptomatic paediatric case of hypocalcaemia, the clinical features of which, and the course after treatment, suggest that it is most probably a case of pseudohypoparathyroidism type Ib.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Female
  • Humans
  • Hypocalcemia / diagnosis*
  • Hypocalcemia / etiology
  • Hypocalcemia / pathology*
  • Pseudohypoparathyroidism / complications