Albumin as a drug delivery and diagnostic tool and its market approved products

Acta Pol Pharm. 2013 Jul-Aug;70(4):597-600.

Abstract

Albumin is one of the most extensively studied endogenous proteins which are used in the fabrication of drug delivery and diagnostic technologies during last 10 years. This review provides a summary of products involving the use of albumin as a drug delivery tool for getting better the pharmacokinetics of a drug by developing the targetted drug delivery systems and diagnosing the pathologies. Using albumin, following market approved products have been developed: Levemir and Victoza (antidiabetic product), Abraxane (antimetastatic breast cancer product), and Nanocoll and Albures (for lymphoscintigraphy and diagnosis of cancer and rheumatoid arthritis).

Publication types

  • Review

MeSH terms

  • Albumin-Bound Paclitaxel
  • Albumins / administration & dosage*
  • Albumins / chemistry
  • Animals
  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / chemistry
  • Chemistry, Pharmaceutical
  • Drug Carriers*
  • Glucagon-Like Peptide 1 / administration & dosage
  • Glucagon-Like Peptide 1 / analogs & derivatives
  • Glucagon-Like Peptide 1 / chemistry
  • Humans
  • Hypoglycemic Agents / administration & dosage
  • Hypoglycemic Agents / chemistry
  • Insulin Detemir
  • Insulin, Long-Acting / administration & dosage
  • Insulin, Long-Acting / chemistry
  • Liraglutide
  • Paclitaxel / administration & dosage
  • Paclitaxel / chemistry
  • Predictive Value of Tests
  • Radiopharmaceuticals
  • Technetium Tc 99m Aggregated Albumin

Substances

  • Albumin-Bound Paclitaxel
  • Albumins
  • Antineoplastic Agents
  • Drug Carriers
  • Hypoglycemic Agents
  • Insulin, Long-Acting
  • Radiopharmaceuticals
  • Technetium Tc 99m Aggregated Albumin
  • technetium Tc 99m nanocolloid
  • Insulin Detemir
  • Liraglutide
  • Glucagon-Like Peptide 1
  • Paclitaxel