Bone mineral density in patients with destructive arthrosis of the hip joint

J Bone Miner Metab. 2014 May;32(3):312-6. doi: 10.1007/s00774-013-0501-6. Epub 2013 Aug 7.

Abstract

Recent reports have shown the existence of subchondral insufficiency fracture in rapidly destructive arthrosis of the hip joint (RDA), and the findings suggest that osteopenia is related to the pathogenesis of the rapid progression of this disease. Therefore, we measured bone mineral density (BMD) in RDA patients. We measured BMD of the lumbar spine, radius, and calcaneus using dual-energy X-ray absorptiometry in 19 patients with RDA and 75 with osteoarthritis of the hip (OA) and compared BMD at different skeletal sites between RDA and OA patients. No significant differences were observed in BMD of the lumbar spine, ultradistal radius, mid-radius, and calcaneous between the RDA and OA groups. Our data suggest that RDA is not accompanied by generalized osteoporosis. Factors other than generalized bone status, for example, BMD around the affected hip joint before destruction, need to be analyzed to elucidate the pathophysiological mechanism of RDA.

MeSH terms

  • Absorptiometry, Photon / methods
  • Aged
  • Aged, 80 and over
  • Bone Density / physiology*
  • Bone Diseases, Metabolic / diagnostic imaging
  • Bone Diseases, Metabolic / pathology
  • Calcaneus / diagnostic imaging
  • Calcaneus / pathology
  • Female
  • Hip / diagnostic imaging
  • Hip / pathology
  • Hip Joint / diagnostic imaging
  • Hip Joint / pathology
  • Humans
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbar Vertebrae / pathology
  • Middle Aged
  • Osteoarthritis, Hip / diagnostic imaging
  • Osteoarthritis, Hip / pathology*
  • Osteoporosis / diagnostic imaging
  • Osteoporosis / pathology