The FREEDOM trial: in appropriate patients with diabetes and multivessel coronary artery disease, CABG beats PCI

Cleve Clin J Med. 2013 Aug;80(8):515-23. doi: 10.3949/ccjm.80a.13030.

Abstract

The Future Revascularization Evaluation in Patients With Diabetes Mellitus: Optimal Management of Multivessel Disease (FREEDOM) trial (N Engl J Med 2012; 367:2375-2384) was designed to resolve the long-standing debate over the optimal revascularization strategy in patients with diabetes mellitus and multivessel coronary artery disease. At a median follow-up of 3.8 years, the incidence of the primary outcome (a composite of death, myocardial infarction, and stroke) was significantly lower with bypass surgery than with percutaneous intervention.

MeSH terms

  • Angioplasty
  • Coronary Artery Bypass*
  • Coronary Artery Disease / complications*
  • Coronary Artery Disease / surgery*
  • Diabetes Complications / complications*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Percutaneous Coronary Intervention*
  • Randomized Controlled Trials as Topic
  • Stents