Saturated treatments and measles resurgence episodes in South Africa: a possible linkage

Math Biosci Eng. 2013 Aug;10(4):1135-57. doi: 10.3934/mbe.2013.10.1135.

Abstract

We consider the case of measles in South Africa to show that an high vaccination coverage may be not enough - alone - to ensure measles eradication. The occurrence of certain epidemic episodes may in fact be encouraged by delays in the treatments or by not adequately fast clinical case management, which may be related to the backward bifurcation phenomenon as well as to an intriguing spiking dynamics which appears in the system for specific ranges of parameter values.

MeSH terms

  • Basic Reproduction Number
  • Epidemics*
  • Humans
  • Measles / epidemiology*
  • Measles / immunology
  • Measles / prevention & control
  • Measles / transmission
  • Measles Vaccine / administration & dosage*
  • Models, Statistical
  • South Africa / epidemiology

Substances

  • Measles Vaccine