Preparation of magnetic rattle-type silica through a general and facile pre-shell-post-core process for simultaneous cancer imaging and therapy

Li Qiang; Xianwei Meng; Linlin Li; Dong Chen; Xiangling Ren; Huiyu Liu; Jun Ren; Changhui Fu; Tianlong Liu; Fuping Gao; Yanqi Zhang; Fangqiong Tang

doi:10.1039/c3cc43660h

Preparation of magnetic rattle-type silica through a general and facile pre-shell-post-core process for simultaneous cancer imaging and therapy

Chem Commun (Camb). 2013 Sep 18;49(72):7902-4. doi: 10.1039/c3cc43660h. Epub 2013 Jul 30.

Authors

Li Qiang¹, Xianwei Meng, Linlin Li, Dong Chen, Xiangling Ren, Huiyu Liu, Jun Ren, Changhui Fu, Tianlong Liu, Fuping Gao, Yanqi Zhang, Fangqiong Tang

Affiliation

¹ Laboratory of Controllable Preparation and Application of Nanomaterials, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, People's Republic of China.

PMID: 23900516
DOI: 10.1039/c3cc43660h

Abstract

Here we report a novel pre-shell-post-core method for the fabrication of monodispersed magnetic rattle-type silica (MRS) through an entrapment process, which could be used as a promising theranostic agent for simultaneous magnetic resonance imaging and drug delivery.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Diagnostic Imaging
Magnetic Resonance Imaging
Magnetics*
Microscopy, Electron, Transmission
Nanoparticles / chemistry*
Neoplasms / diagnosis
Neoplasms / therapy
Silicon Dioxide / chemistry*

Substances

Silicon Dioxide