Abstract
Azomethine imines can be accessed upon heating appropriate alkynylhydrazide precursors. This simple thermal hydroamination approach allows the formation of five- and six-membered dipoles in modest to excellent yields. The structure of the acyl group is important to minimize side reactions and allow the isolation of the azomethine imines by column chromatography.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkynes / chemistry*
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Azo Compounds / chemical synthesis*
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Azo Compounds / chemistry
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Hydralazine / chemistry*
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Imines / chemical synthesis*
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Imines / chemistry
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Molecular Structure
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Thiosemicarbazones / chemical synthesis*
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Thiosemicarbazones / chemistry
Substances
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Alkynes
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Azo Compounds
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Imines
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Thiosemicarbazones
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azomethine
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Hydralazine