A child with altered sensorium, hyperglycemia, and elevated troponins

J Emerg Med. 2014 Feb;46(2):184-90. doi: 10.1016/j.jemermed.2013.05.019. Epub 2013 Jul 21.

Abstract

Background: Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) are potentially life-threatening complications of diabetes mellitus. Although DKA and HHS share similar features, they are distinct clinical entities requiring different treatment measures.

Objective: This case illustrates that the clinical distinction between these two entities can be difficult at times, especially in children who can present with an overlapping picture.

Case report: We report an interesting case of a 12-year-old whose initial presentation of diabetes was a mixed picture of hyperosmolar DKA and HHS coma complicated by myocardial strain and acute renal insufficiency. The myocardial strain resolved completely with resolution of the metabolic abnormalities.

Conclusions: Emergency physicians should be cognizant of varied presentations of hyperglycemic emergencies in children to initiate appropriate management for better outcomes.

Keywords: altered sensorium; children; hyperglycemia; troponin.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acute Disease
  • Brain Edema / diagnosis
  • Child
  • Diabetes Mellitus, Type 1 / complications*
  • Diabetic Ketoacidosis / diagnosis*
  • Humans
  • Hyperglycemia / diagnosis*
  • Male
  • Myocardial Infarction / blood
  • Risk Factors
  • Sensation Disorders / diagnosis*
  • Troponin / blood*

Substances

  • Troponin