Efficient α-helix induction in a linear peptide chain by N-capping with a bridged-tricyclic diproline analogue

Angew Chem Int Ed Engl. 2013 Sep 2;52(36):9539-43. doi: 10.1002/anie.201302014. Epub 2013 Jul 19.
No abstract available

Keywords: conformational analysis; molecular modeling; peptides and peptide mimics; protein-protein interactions; ring-closing metathesis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Circular Dichroism
  • Crystallography, X-Ray
  • Cyclization
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Peptides / chemistry*
  • Proline / chemistry*
  • Protein Structure, Secondary

Substances

  • Peptides
  • Proline