Glia keep synapse distribution under wraps

Cell. 2013 Jul 18;154(2):267-8. doi: 10.1016/j.cell.2013.06.045.

Abstract

The wiring of the nervous system requires that axons navigate to the correct targets and maintain their correct positions during developmental growth. In this issue, Shao et al. (2013) now reveal a crucial new role for glia in preserving correct synaptic connectivity during developmental growth.

Publication types

  • Comment

MeSH terms

  • Animals
  • Caenorhabditis elegans / growth & development*
  • Caenorhabditis elegans / metabolism*
  • Caenorhabditis elegans Proteins / metabolism*
  • Neuroglia / metabolism*
  • Receptors, Fibroblast Growth Factor / metabolism*
  • Sodium-Phosphate Cotransporter Proteins, Type I / metabolism*
  • Synapses*

Substances

  • CIMA-1 protein, C elegans
  • Caenorhabditis elegans Proteins
  • EGL-15 protein, C elegans
  • Receptors, Fibroblast Growth Factor
  • Sodium-Phosphate Cotransporter Proteins, Type I