Genetically engineered peptides for inorganics: study of an unconstrained bacterial display technology and bulk aluminum alloy

Abstract

The first-ever peptide biomaterial discovery using an unconstrained engineered bacterial display technology is reported. Using this approach, we have developed genetically engineered peptide binders for a bulk aluminum alloy and use molecular dynamics simulation of peptide conformational fluctuations to demonstrate sequence-dependent, structure-function relationships for metal and metal oxide interactions.

Keywords: GEPI; biomineralization; biopanning; molecular dynamics; peptide display; solid-binding peptide.