[Dimethyl sulfoxide as a corrector of disorders of cerebral hemodynamics, oxygen and carbohydrate metabolism of the brain and lipid peroxidation in the early period after intracerebral hemorrhage]

Abstract

Intraperitoneal injection of DMSO (0.7 g/kg) in rats 1h after intracerebral hemorrhage prevented brain conjugated diens and fluorosciene products increase and limited cerebral ++anti-radical activity. In experiments on cats 1h after intracerebral hemorrhage intravenous infusion of DMSO (0.3 g/kg) for 30 min improved cerebral hemodynamic, oxygen and glucose metabolism; cats mortality was decreased.