Abstract
The review describes the mechanisms of hormonal, autocrine, paracrine and intracellular regulation in osteogenic differentiation of mesenchymal stem cells, the role of negative feedbacks in this process.
MeSH terms
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Animals
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Bone Marrow Cells / cytology
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Cell Differentiation*
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Fibroblast Growth Factors / genetics
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Fibroblast Growth Factors / metabolism
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Humans
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Intercellular Signaling Peptides and Proteins / metabolism
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Mesenchymal Stem Cells / cytology
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Mesenchymal Stem Cells / physiology*
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Microscopy, Electron, Scanning Transmission
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Osteoblasts / cytology
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Osteoblasts / metabolism
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Osteogenesis / genetics*
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Osteogenesis / physiology
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Wnt Signaling Pathway / genetics
Substances
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Intercellular Signaling Peptides and Proteins
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Fibroblast Growth Factors