Advanced MR imaging of gliomas: an update

Biomed Res Int. 2013:2013:970586. doi: 10.1155/2013/970586. Epub 2013 Jun 4.

Abstract

Recent advances in the treatment of cerebral gliomas have increased the demands on noninvasive neuroimaging for the diagnosis, therapeutic planning, tumor monitoring, and patient outcome prediction. In the meantime, improved magnetic resonance (MR) imaging techniques have shown much potentials in evaluating the key pathological features of the gliomas, including cellularity, invasiveness, mitotic activity, angiogenesis, and necrosis, hence, further shedding light on glioma grading before treatment. In this paper, an update of advanced MR imaging techniques is reviewed, and their potential roles as biomarkers of tumor grading are discussed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Brain Neoplasms / blood supply
  • Brain Neoplasms / diagnosis*
  • Brain Neoplasms / pathology
  • Glioma / blood supply
  • Glioma / diagnosis*
  • Glioma / pathology
  • Humans
  • Magnetic Resonance Imaging*
  • Mitosis
  • Neoplasm Invasiveness
  • Neovascularization, Pathologic / diagnosis