A 5 mo old male golden retriever presented for evaluation of an acute onset, progressive neurologic disease. Although computed tomography (CT) was unremarkable, MRI identified an ill-defined mass located in the medulla, which was considered likely responsible for the clinical signs. The imaging features closely resembled the classic features of human brainstem gliomas in the pediatric population. Histopathologic examination confirmed the lesion to be an anaplastic oligodendroglioma.