Comparisons between autism spectrum disorders and anxiety disorders: findings from a clinic sample in Singapore

Asia Pac Psychiatry. 2014 Mar;6(1):46-53. doi: 10.1111/j.1758-5872.2012.00228.x. Epub 2012 Sep 7.

Abstract

Introduction: The goals of the present study were to: (i) examine similarities and differences in behavioral/emotional problems manifested by children with autism spectrum disorder (ASD) and those with anxiety disorder (ANX); (ii) test the ability of each of the eight child behavioral checklist (CBCL) and teacher report form (TRF) syndrome scales to differentiate the ASD group from the ANX group; and (iii) test the ability of an ASD scale derived by Ooi et al. to differentiate the ASD group from the ANX group.

Methods: Archival CBCL and TRF data from 180 children between 4 and 18 years of age (119 males, 61 females) diagnosed with ASD (n = 86) or ANX (n = 94) at an outpatient child psychiatric clinic in Singapore were analyzed.

Results: The ASD group scored significantly higher on Social Problems and Attention Problems but significantly lower on Anxious/Depressed and Somatic Complaints than the ANX group. The groups did not show significant differences on Withdrawn/Depressed and Thought Problems. Both the CBCL and TRF ASD scales were significant predictors of the ASD group, with moderate to high sensitivity and specificity.

Discussion: Our findings for an Asian sample support the diagnostic overlap between ASD and ANX reported for Western samples and underscore the importance of treating ASD as both a unitary disease and as a web of overlapping configurations of underlying problem dimensions.

Keywords: anxiety disorder; autism spectrum disorder; child behavior checklist; teacher report form.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Analysis of Variance
  • Anxiety Disorders / diagnosis*
  • Anxiety Disorders / psychology
  • Attention
  • Child
  • Child Behavior / psychology
  • Child Development Disorders, Pervasive / diagnosis*
  • Child Development Disorders, Pervasive / psychology
  • Child, Preschool
  • Diagnosis, Differential
  • Emotions / physiology
  • Female
  • Humans
  • Interpersonal Relations
  • Male
  • Psychiatric Status Rating Scales