Objective: To be acquainted with genetic characteristics and variation of mumps virus strains circulating in Hunan province.
Methods: Mumps virus (MV) strains were isolated using Vero/ SLAM cells. The small hydrophobic protein (SH) genes of MV isolates were sequenced, and the sequences were analysed phylogenetically between the isolated strains and other reference mumps strains.
Results: 4 mumps virus strains were isolated from 16 specimens collected in 2011 from different regions of Hunan province. The genotype of isolated strains were supposed to be F type.
Conclusion: Genotype F is the main genotype of circulating strains in Hunan province in 2011 and there is no variation between genotype.