Gastrointestinal stromal tumors (GIST): lesser known facts

Abstract

In an era of molecular targeted therapy, patients with advanced gastrointestinal stromal tumor (GIST) are living longer and are often followed with imaging. Therefore, it is important for the radiologists to be aware of the atypical subtypes of GIST, implications of molecular makeup, its behavior, and the uncommon metastatic sites. The aim of this pictorial review is to illustrate the lesser-known aspects of GIST including histological and molecular classifications, syndromes associated with GIST, and uncommon metastatic sites.

Keywords: Atypical metastases; Gastrointestinal stromal tumor; Molecular classification; Syndromes associated with GIST; Tumor biology.