Tumor angiogenesis: a new source of pericytes

Curr Biol. 2013 Jul 8;23(13):R565-8. doi: 10.1016/j.cub.2013.05.023.

Abstract

Glioblastoma stem cells have been reported to directly contribute to the tumor vasculature by endothelial cell differentiation. Interestingly, a recent study demonstrates that glioblastoma stem cells preferentially differentiate into vascular pericytes to support vasculature function and tumor growth.

Publication types

  • Comment

MeSH terms

  • Animals
  • Brain Neoplasms / pathology*
  • Glioblastoma / pathology*
  • Humans
  • Neoplastic Stem Cells / pathology*
  • Pericytes / pathology*