Ruthenium-catalyzed intramolecular allylic dearomatization reaction of indole derivatives

Xiao Zhang; Wen-Bo Liu; Qing-Feng Wu; Shu-Li You

doi:10.1021/ol4016578

Ruthenium-catalyzed intramolecular allylic dearomatization reaction of indole derivatives

Org Lett. 2013 Jul 19;15(14):3746-9. doi: 10.1021/ol4016578. Epub 2013 Jul 10.

Authors

Xiao Zhang¹, Wen-Bo Liu, Qing-Feng Wu, Shu-Li You

Affiliation

¹ State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China.

PMID: 23841581
DOI: 10.1021/ol4016578

Abstract

An efficient synthesis of spiroindolenine derivatives via a ruthenium-catalyzed intramolecular allylic dearomatization reaction has been developed. This method features a wide substrate scope, mild reaction conditions, and an operationally simple procedure.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Indoles / chemical synthesis*
Indoles / chemistry*
Molecular Structure
Ruthenium / chemistry*
Spiro Compounds / chemical synthesis*
Spiro Compounds / chemistry*
Stereoisomerism

Substances

Indoles
Spiro Compounds
Ruthenium