Linear immunoglobulin a bullous dermatosis: need for an agreement on diagnostic criteria

Dermatology. 2013;226(4):329-32. doi: 10.1159/000350818. Epub 2013 Jul 3.

Abstract

Linear immunoglobulin A bullous dermatosis (LABD) is a rare, heterogeneous, autoimmune blistering disorder. Although the main characteristics of the disease seem to be well identified, international accepted diagnostic criteria are lacking. Several authors suggested their own criteria, but they are often not complete or even in contrast with clinical and immunopathological findings from the literature, while others are too selective. In this review, the current views and the problems with the definition of reliable diagnostic criteria for LABD will be discussed.

Publication types

  • Editorial
  • Review

MeSH terms

  • Basement Membrane
  • Fluorescent Antibody Technique
  • Humans
  • Immunoglobulin A
  • Linear IgA Bullous Dermatosis / diagnosis*
  • Linear IgA Bullous Dermatosis / pathology

Substances

  • Immunoglobulin A