Abstract
Stannous fluoride has a long history of use in the improvement of oral health, and was the fluoride source first proven to provide anti-caries benefits when delivered from a dentrifrice formulation. This paper provides an account of the early use of stannous fluoride, primarily for an anti-caries benefit, and the subsequent attempts to formulate stannous fluoride into stable formulations where additional benefits of the stannous cation can be realized.
MeSH terms
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Calcium Pyrophosphate / therapeutic use
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Dental Caries / prevention & control
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Dentifrices / chemical synthesis
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Dentifrices / chemistry
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Dentifrices / therapeutic use*
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Dentin Sensitivity / drug therapy*
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Drug Combinations
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Fluorides / therapeutic use
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Humans
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Phosphates / therapeutic use
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Polyphosphates / therapeutic use
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Tin Fluorides / chemical synthesis
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Tin Fluorides / chemistry
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Tin Fluorides / therapeutic use*
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Tooth Discoloration / prevention & control
Substances
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Dentifrices
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Drug Combinations
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Phosphates
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Polyphosphates
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Tin Fluorides
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fluorophosphate
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triphosphoric acid
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Fluorides
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Calcium Pyrophosphate