1,2,3-Triazoles as amide bond mimics: triazole scan yields protease-resistant peptidomimetics for tumor targeting

Angew Chem Int Ed Engl. 2013 Aug 19;52(34):8957-60. doi: 10.1002/anie.201303108. Epub 2013 Jul 5.

Authors

Ibai E Valverde¹, Andreas Bauman, Christiane A Kluba, Sandra Vomstein, Martin A Walter, Thomas L Mindt

Affiliation

¹ Department of Radiology and Nuclear Medicine, Division of Radiopharmaceutical Chemistry, University of Basel Hospital, Petersgraben 4, 4031 Basel, Switzerland.

PMID: 23832715
DOI: 10.1002/anie.201303108

No abstract available

Keywords: click chemistry; drug delivery; metabolic stabilization; peptidomimetics; radiopharmaceuticals.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amides
Humans
Neoplasms / chemistry
Neoplasms / immunology*
Peptidomimetics / chemistry*
Triazoles / chemistry*

Substances

Amides
Peptidomimetics
Triazoles