Detectability of simulated pulmonary nodules on chest radiographs: comparison between irradiation side sampling indirect flat-panel detector and computed radiography

Eur J Radiol. 2013 Nov;82(11):2050-4. doi: 10.1016/j.ejrad.2013.05.036. Epub 2013 Jul 1.

Abstract

Objective: To compare the detectability of simulated pulmonary nodules on chest radiographs between an irradiation side sampling indirect flat-panel detector (ISS-FPD) and computed radiography (CR).

Materials and methods: This study was an observer performance study. Simulated pulmonary nodules of 8 mm in diameter were superimposed on an anthropomorphic chest phantom. Chest radiographs were acquired under 2 exposure levels (4 and 3.2 mAs) with the ISS-FPD and the CR. Six thoracic radiologists evaluated all 40 images (10 patterns × 2 different exposure doses × 2 different systems) for the presence or absence of a lesion over each of 12 defined areas on a 3-megapixel monochrome liquid-crystal display. Receiver operating characteristic (ROC) curves were obtained for observation in predefined 480 areas. A jackknife method was used for statistical analysis. Differences with a P value of <0.05 were considered significant.

Results: The analysis of the observer detection of simulated pulmonary nodules showed larger areas under the ROC curve (AUC) by the ISS-FPD than by the CR. There was a statistically significant difference between the two systems at 3.2 mAs (P=0.0330).

Conclusion: The ISS-FPD was superior to the CR for the detection of simulated pulmonary nodules at 3.2 mAs.

Keywords: Diagnostic performance; Imaging; Phantoms; ROC curve; Radiographic image enhancement; Solitary pulmonary nodule.

Publication types

  • Comparative Study
  • Observational Study

MeSH terms

  • Equipment Design
  • Equipment Failure Analysis
  • Humans
  • Image Enhancement / instrumentation*
  • Observer Variation
  • Phantoms, Imaging*
  • Radiation Dosage
  • Radiography, Thoracic / instrumentation*
  • Reproducibility of Results
  • Sample Size
  • Sensitivity and Specificity
  • Solitary Pulmonary Nodule / diagnostic imaging*
  • Tomography, X-Ray Computed / instrumentation*
  • X-Ray Intensifying Screens