Positional dependency and surgical success of relocation pharyngoplasty among patients with severe obstructive sleep apnea

Otolaryngol Head Neck Surg. 2013 Sep;149(3):506-12. doi: 10.1177/0194599813495663. Epub 2013 Jul 1.

Abstract

Objective: To examine the effect of positional dependency on surgical success among patients with severe obstructive sleep apnea (OSA) following modified uvulopalatopharyngoplasty, known as relocation pharyngoplasty.

Study design: Case series with planned data collection.

Setting: Tertiary referred center.

Subjects and methods: Standard nocturnal polysomnography was used to compare the apnea-hypopnea index (AHI) in different sleep positions before and after relocation pharyngoplasty in 47 consecutive patients with severe OSA (AHI, 59.5 ± 18.2 events/hour; Epworth Sleepiness Scale [ESS] scores, 12.2 ± 4.4) who failed continuous positive airway pressure therapy. Positional (dependency) OSA was defined when the supine:non-supine AHI ratio was >2, otherwise it was defined as nonpositional OSA. Surgical success was defined as a ≥50% reduction in AHI and a postoperative AHI of ≤20 events/hour. Polysomnographic parameters, ESS, and surgical success following surgery were recorded.

Results: Of the 47 patients, 27 (57%) had positional OSA and 20 (43%) nonpositional OSA. The nonpositional OSA patients had higher AHI and ESS scores than the positional OSA patients (P = .002 and .104, respectively). Relocation pharyngoplasty significantly improved AHI and ESS scores in both positional and nonpositional OSA groups 6 months postoperatively (P < .05). The overall surgical success rate was 49%; however, positional OSA patients had a significantly higher success rate than nonpositional OSA patients (67% vs 25%, P = .008).

Conclusion: The presence of positional dependency at baseline was a favorable outcome predictor of surgical success among severe OSA patients undergoing relocation pharyngoplasty.

Keywords: obstructive sleep apnea; outcome; positional dependency; relocation pharyngoplasty; sleep position.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Female
  • Humans
  • Male
  • Pharynx / physiopathology
  • Pharynx / surgery*
  • Polysomnography
  • Posture / physiology*
  • Prognosis
  • Retrospective Studies
  • Severity of Illness Index
  • Sleep Apnea, Obstructive / physiopathology
  • Sleep Apnea, Obstructive / surgery*
  • Treatment Outcome