Abstract
We did a retrospective review of children with Mycoplasma pneumoniae infection hospitalized from March 2010 to March 2013. Mycoplasma-resistant M. pneumoniae constituted 70% of the total M. pneumoniae-associated community-acquired pneumonia. Doxycycline was significantly more effective than macrolide for treatment of Mycoplasma-resistant M. pneumoniae-associated community-acquired pneumonia in terms of achievement of rapid defervescence within 24 hours.
MeSH terms
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Adolescent
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Anti-Bacterial Agents / pharmacology
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Anti-Bacterial Agents / therapeutic use*
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Child
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Child, Preschool
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Community-Acquired Infections / drug therapy*
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Community-Acquired Infections / epidemiology
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Community-Acquired Infections / microbiology*
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Doxycycline / therapeutic use*
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Drug Resistance, Bacterial
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Female
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Fever / microbiology
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Hong Kong / epidemiology
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Humans
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Macrolides / pharmacology
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Macrolides / therapeutic use*
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Male
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Mycoplasma pneumoniae / drug effects
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Pneumonia, Mycoplasma / drug therapy*
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Pneumonia, Mycoplasma / epidemiology
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Pneumonia, Mycoplasma / microbiology*
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Retrospective Studies
Substances
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Anti-Bacterial Agents
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Macrolides
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Doxycycline