Clinical value of 2-deoxy-[18F]fluoro-D-glucose positron emission tomography in patients with cervical spondylotic myelopathy

Neurosurg Focus. 2013 Jul;35(1):E2. doi: 10.3171/2013.3.FOCUS1379.

Abstract

Cervical spondylotic myelopathy (CSM) is one of the most common spinal cord disorders in the elderly. It is usually diagnosed by MRI, but in a significant number of patients the clinical course of CSM does not correlate with the extent of the spinal cord compression. Recent studies have suggested that a distinct metabolic pattern of the cervical cord, as assessed by PET with 2-deoxy-[(18)F]fluoro-D-glucose ((18)F-FDG) may predict a patient's clinical outcome after decompressive surgery for cervical spine stenosis. The authors provide an overview of the recent literature regarding the value of PET with (18)F-FDG of the cervical cord in patients with CSM, paying attention to prognostic aspects and the potential role of inflammatory processes in the acute phase of the disease.

Publication types

  • Review

MeSH terms

  • Cervical Vertebrae / diagnostic imaging*
  • Cervical Vertebrae / metabolism
  • Cervical Vertebrae / pathology
  • Fluorodeoxyglucose F18* / metabolism
  • Humans
  • Magnetic Resonance Imaging / methods
  • Magnetic Resonance Imaging / standards
  • Positron-Emission Tomography / methods*
  • Positron-Emission Tomography / standards
  • Spinal Cord Diseases / diagnostic imaging*
  • Spinal Cord Diseases / metabolism
  • Spondylosis / diagnostic imaging*
  • Spondylosis / metabolism

Substances

  • Fluorodeoxyglucose F18