Host-lipidome as a potential target of protozoan parasites

Microbes Infect. 2013 Sep-Oct;15(10-11):649-60. doi: 10.1016/j.micinf.2013.06.006. Epub 2013 Jun 27.

Abstract

Host-lipidome caters parasite interaction by acting as first line of recognition, attachment on the cell surface, intracellular trafficking, and survival of the parasite inside the host cell. Here, we summarize how protozoan parasites exploit host-lipidome by suppressing, augmenting, engulfing, remodeling and metabolizing lipids to achieve successful parasitism inside the host.

Keywords: Bioactive lipids; Enzymes; Host-lipidome; Membrane; Protozoans.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Apicomplexa / metabolism*
  • Host-Parasite Interactions*
  • Humans
  • Lipid Metabolism*
  • Trypanosomatina / metabolism*