Nanotechnology-based restorative materials for dental caries management

Trends Biotechnol. 2013 Aug;31(8):459-67. doi: 10.1016/j.tibtech.2013.05.010. Epub 2013 Jun 28.

Abstract

Nanotechnology has been applied to dental materials as an innovative concept for the development of materials with better properties and anticaries potential. In this review we discuss the current progress and future applications of functional nanoparticles incorporated in dental restorative materials as useful strategies to dental caries management. We also overview proposed antimicrobial and remineralizing mechanisms. Nanomaterials have great potential to decrease biofilm accumulation, inhibit the demineralization process, to be used for remineralizing tooth structure, and to combat caries-related bacteria. These results are encouraging and open the doors to future clinical studies that will allow the therapeutic value of nanotechnology-based restorative materials to be established.

Keywords: dental caries; dental materials; nanoparticles; nanotechnology.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / therapeutic use
  • Biotechnology / methods*
  • Dental Caries / therapy*
  • Dental Materials / chemistry*
  • Dental Materials / therapeutic use*
  • Humans
  • Nanotechnology / methods*
  • Tooth Remineralization / methods*

Substances

  • Anti-Bacterial Agents
  • Dental Materials