Asymmetric Ti-crossed Claisen condensation: application to concise asymmetric total synthesis of alternaric acid

Ryohei Nagase; Yumiko Oguni; Satoko Ureshino; Hiroaki Mura; Tomonori Misaki; Yoo Tanabe

doi:10.1039/c3cc43180k

Asymmetric Ti-crossed Claisen condensation: application to concise asymmetric total synthesis of alternaric acid

Chem Commun (Camb). 2013 Aug 11;49(62):7001-3. doi: 10.1039/c3cc43180k.

Authors

Ryohei Nagase¹, Yumiko Oguni, Satoko Ureshino, Hiroaki Mura, Tomonori Misaki, Yoo Tanabe

Affiliation

¹ Department of Chemistry, School of Science and Technology, Kwansei Gakuin University, 2-1 Gakuen, Sanda, Hyogo 669-1337, Japan.

PMID: 23807372
DOI: 10.1039/c3cc43180k

Abstract

Asymmetric Ti-crossed Claisen condensation utilizing the dioxane-2,5-dione chiral template and its successful application to total synthesis of chiral alternaric acid are described.

MeSH terms

Acids / chemical synthesis*
Acids / chemistry
Molecular Structure
Titanium / chemistry*

Substances

Acids
Titanium