Polar body biopsy

Markus Montag; Maria Köster; Thomas Strowitzki; Bettina Toth

doi:10.1016/j.fertnstert.2013.05.053

Polar body biopsy

Fertil Steril. 2013 Sep;100(3):603-7. doi: 10.1016/j.fertnstert.2013.05.053. Epub 2013 Jun 21.

Authors

Markus Montag¹, Maria Köster, Thomas Strowitzki, Bettina Toth

Affiliation

¹ Department of Gynecologic Endocrinology and Fertility Disorders, Ruprecht-Karls University Heidelberg, Heidelberg, Germany. mmontag@ilabcomm.com

PMID: 23796365
DOI: 10.1016/j.fertnstert.2013.05.053

Abstract

Polar body biopsy combined with array comparative genomic hybridization allows detection of maternal chromosomal aberrations. Although it has limitations, it can be seen as an alternative to blastomere and trophectoderm biopsy.

Keywords: PGS; Polar body biopsy; aneuploidy; array-CGH; oocyte.

Publication types

Review

MeSH terms

Biopsy / methods
Comparative Genomic Hybridization / methods
Cytogenetic Analysis / methods
Female
Humans
In Situ Hybridization, Fluorescence / methods
Polar Bodies / pathology*
Predictive Value of Tests
Pregnancy
Prenatal Diagnosis / methods*