Synthesis of heterogeneous enzyme-metal nanoparticle biohybrids in aqueous media and their applications in C-C bond formation and tandem catalysis

Chem Commun (Camb). 2013 Aug 7;49(61):6876-8. doi: 10.1039/c3cc42475h. Epub 2013 Jun 24.

Abstract

The straightforward synthesis of novel enzyme-metalNP nanobiohybrids in aqueous medium was developed. These new nanobiohybrids were excellent multivalent catalysts combining both activities in various sets of synthetic reactions even at ultra-low concentrations (ppb amount).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocatalysis
  • Fungal Proteins / chemistry
  • Fungal Proteins / metabolism*
  • Gold / chemistry
  • Gold / metabolism*
  • Lipase / chemistry
  • Lipase / metabolism*
  • Metal Nanoparticles / chemistry*
  • Models, Molecular
  • Palladium / chemistry
  • Palladium / metabolism*
  • Particle Size
  • Silver / chemistry
  • Silver / metabolism*
  • Surface Properties
  • Water / chemistry
  • Water / metabolism

Substances

  • Fungal Proteins
  • Water
  • Silver
  • Palladium
  • Gold
  • Lipase
  • lipase B, Candida antarctica