Does germ-line deletion of the PIP gene constitute a widespread risk for cancer?

Eur J Hum Genet. 2014 Mar;22(3):307-9. doi: 10.1038/ejhg.2013.134. Epub 2013 Jun 19.

Authors

Amanda G Silva¹, Ana C V Krepischi¹, Giovana T Torrezan¹, Leonardo P Capelli¹, Dirce M Carraro¹, Carla S D'Angelo², Celia P Koiffmann², Mayana Zatz², Michel S Naslavsky², Cibele Masotti², Paulo A Otto², Maria I W Achatz¹, Ryan E Mills³, Charles Lee⁴, Peter L Pearson², Carla Rosenberg²

Affiliations

¹ A.C. Camargo Cancer Center, São Paulo, Brazil.
² Department of Genetics and Evolutionary Biology, Institute of Biosciences, University of São Paulo, São Paulo, Brazil.
³ 1] Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA [2] Department of Computational Medicine & Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, USA.
⁴ Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adenomatous Polyposis Coli / diagnosis
Adenomatous Polyposis Coli / genetics*
Adolescent
Adult
Age of Onset
Aged
Carrier Proteins / genetics*
Case-Control Studies
Child
DNA Copy Number Variations
Gene Deletion
Genetic Predisposition to Disease
Germ-Line Mutation*
Glycoproteins / genetics*
Humans
Li-Fraumeni Syndrome / genetics*
Membrane Transport Proteins
Middle Aged
Receptors, Cell Surface / genetics
Tumor Suppressor Protein p53 / genetics

Substances

Carrier Proteins
Glycoproteins
Membrane Transport Proteins
PIP protein, human
Receptors, Cell Surface
TAS2R39 protein, human
Tumor Suppressor Protein p53