Abstract
A highly sensitive and rapid PCR-free telomerase activity assay has been developed that uses SYBR Green intercalation into the G-quadruplex structures in the presence of K(+).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anthraquinones / pharmacology
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Benzothiazoles
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Cell Line
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Diamines
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G-Quadruplexes
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HEK293 Cells
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HeLa Cells
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Hep G2 Cells
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Humans
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Organic Chemicals / chemistry
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Organic Chemicals / metabolism
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Potassium / chemistry
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Quinolines
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Structure-Activity Relationship
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Telomerase / antagonists & inhibitors
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Telomerase / chemistry
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Telomerase / metabolism*
Substances
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Anthraquinones
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Benzothiazoles
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Diamines
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Organic Chemicals
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Quinolines
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SYBR Green I
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2,6-diaminoanthraquinone
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Telomerase
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Potassium