Molecular epidemiologic source tracking of orally transmitted Chagas disease, Venezuela

Emerg Infect Dis. 2013 Jul;19(7):1098-101. doi: 10.3201/eid1907.121576.

Abstract

Oral outbreaks of Chagas disease are increasingly reported in Latin America. The transitory presence of Trypanosoma cruzi parasites within contaminated foods, and the rapid consumption of those foods, precludes precise identification of outbreak origin. We report source attribution for 2 peri-urban oral outbreaks of Chagas disease in Venezuela via high resolution microsatellite typing.

Keywords: Caracas; Chagas disease; Trypanosoma cruzi; Vargas State; Venezuela; molecular epidemiology; oral; orally transmitted; parasites; trypanosome; vector-borne infections; zoonoses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Antibodies, Protozoan / blood
  • Chagas Disease / blood
  • Chagas Disease / epidemiology*
  • Chagas Disease / parasitology
  • Chagas Disease / transmission
  • Child
  • Cluster Analysis
  • Contact Tracing
  • Discriminant Analysis
  • Disease Outbreaks
  • Genes, Protozoan
  • Humans
  • Microsatellite Repeats
  • Molecular Epidemiology
  • Molecular Typing
  • Phylogeny
  • Principal Component Analysis
  • Trypanosoma cruzi / genetics*
  • Trypanosoma cruzi / immunology
  • Venezuela / epidemiology

Substances

  • Antibodies, Protozoan