Use of β-alanine as an ergogenic aid

Nestle Nutr Inst Workshop Ser. 2013:75:99-108. doi: 10.1159/000345825. Epub 2013 Apr 16.

Abstract

Despite the large variety of so-called ergogenic supplements used by the sporting community, only few of them are effectively supported by scientific proof. One of the recent evidence-based supplements that entered the market is β-alanine. β-Alanine is the rate-limiting precursor for the synthesis of the dipeptide carnosine (β-alanyl-L-histidine) in human muscle. The chronic daily ingestion of β-alanine can markedly elevate muscle carnosine content, which results in improved exercise capacity, especially in sports that include high-intensity exercise episodes. The use of β-alanine is exponentially growing in recent years. This chapter aims to (1) discuss the scientific basis and physiological background of β-alanine and its synthesis product carnosine, and (2) translate these scientific findings to practical applications in sports.

MeSH terms

  • Acidosis / drug therapy
  • Bicarbonates / administration & dosage
  • Carnosine / metabolism
  • Dietary Supplements*
  • Exercise / physiology
  • Humans
  • Muscle, Skeletal / drug effects
  • Muscle, Skeletal / metabolism
  • Sports Nutritional Physiological Phenomena*
  • beta-Alanine / administration & dosage*

Substances

  • Bicarbonates
  • beta-Alanine
  • Carnosine