A general strategy for the generation of hypoallergenic molecules for the immunotherapy of fish allergy

J Allergy Clin Immunol. 2013 Oct;132(4):979-81.e1. doi: 10.1016/j.jaci.2013.04.027. Epub 2013 Jun 12.

Authors

Ines Swoboda¹, Nadja Balic, Christoph Klug, Margit Focke, Milena Weber, Susanne Spitzauer, Angela Neubauer, Santiago Quirce, Nikolaos Douladiris, Nikolaos G Papadopoulos, Rudolf Valenta

Affiliation

¹ Christian Doppler Laboratory for Allergy Research, Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Austria; Molecular Biotechnology Section, University of Applied Sciences, Campus Vienna Biocenter, Vienna, Austria. Electronic address: ines.swoboda@meduniwien.ac.at.

PMID: 23763969
DOI: 10.1016/j.jaci.2013.04.027

No abstract available

Publication types

Evaluation Study
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Allergens / chemistry
Allergens / genetics
Allergens / immunology*
Allergens / metabolism
Amino Acid Sequence
Animals
Cross Reactions
Desensitization, Immunologic / methods*
Fish Proteins / chemistry
Fish Proteins / genetics
Fish Proteins / immunology*
Fish Proteins / metabolism
Fishes / classification
Fishes / immunology*
Food Hypersensitivity / etiology
Food Hypersensitivity / therapy*
Humans
Immunoglobulin E / blood
Molecular Sequence Data
Mutation
Parvalbumins / chemistry
Parvalbumins / genetics
Parvalbumins / immunology*
Parvalbumins / metabolism

Substances

Allergens
Fish Proteins
Parvalbumins
Immunoglobulin E