Rim15p-mediated regulation of sucrose utilization during molasses fermentation using Saccharomyces cerevisiae strain PE-2

Abstract

Inherited loss-of-function mutations in the Rim15p-mediated stress-response pathway contribute to the high fermentation rate of sake yeast strains. In the present study, we found that disruption of the RIM15 gene in ethanol-producing Saccharomyces cerevisiae strain PE-2 accelerated molasses fermentation through enhanced sucrose utilization following glucose starvation.

Keywords: Alcoholic fermentation; Msn2p; Rim15p; Saccharomyces cerevisiae; Sake yeast; Stress response; Sucrose utilization; Sugarcane molasses.