Thyroxine, shape, and weight: interaction of Graves' disease and bulimia nervosa

Eat Weight Disord. 2013 Mar;18(1):99-101. doi: 10.1007/s40519-013-0013-3. Epub 2013 Mar 29.

Abstract

Objective: A case of a 25-year-old woman with bulimia nervosa and Graves' disease is presented. Graves' disease is the cause of 50-80 % of hyperthyroidism. The disease is characterized by increases of thyroid hormone production, activation of the metabolism, and successive weight loss. Bulimia nervosa is characterized by purging behavior after binge eating episodes.

Method and results: We report a patient suffering from both entities. A pronounced non-compliance to the intake of antithyroid drugs (Carbimazole) correlated with eating disorder symptoms like negative evaluation of the body and fear of weight gain. Thus, elevated hyperthyroidism due to Graves' disease served as a purging method. During 8 weeks of inpatient psychotherapy, the patient adapted to a structured eating behavior. Self-esteem was less influenced by body shape and body weight, and compliance to endocrinological recommendations improved.

Conclusion: Non-compliance to antithyroid drugs may be a symptom of an eating disorder. A careful and primarily non-confronting interdisciplinary diagnostic and treatment approach is required.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antithyroid Agents / therapeutic use
  • Body Image / psychology*
  • Bulimia Nervosa / complications*
  • Bulimia Nervosa / psychology
  • Bulimia Nervosa / therapy
  • Carbimazole / therapeutic use
  • Cognitive Behavioral Therapy
  • Female
  • Graves Disease / complications*
  • Graves Disease / drug therapy
  • Graves Disease / psychology
  • Humans
  • Medication Adherence / psychology*
  • Self Concept*
  • Treatment Outcome

Substances

  • Antithyroid Agents
  • Carbimazole