In rare acute myeloid leukemia patients harboring both RUNX1 and NPM1 mutations, RUNX1 mutations are unusual in structure and present in the germline

Haematologica. 2013 Aug;98(8):e92-4. doi: 10.3324/haematol.2013.089904. Epub 2013 Jun 10.
No abstract available

Keywords: NPM1; RUNX1; acute myeloid leukemia; mutational interrelationships; mutations.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Core Binding Factor Alpha 2 Subunit / genetics*
  • Female
  • Germ-Line Mutation / genetics*
  • Humans
  • Leukemia, Myeloid, Acute / diagnosis*
  • Leukemia, Myeloid, Acute / genetics*
  • Male
  • Middle Aged
  • Nuclear Proteins / genetics*
  • Nucleophosmin

Substances

  • Core Binding Factor Alpha 2 Subunit
  • NPM1 protein, human
  • Nuclear Proteins
  • RUNX1 protein, human
  • Nucleophosmin