Aim: to discuss the rationale of the management of penile MALT lymphoma.
Case report: A 24-year-old patient presented with a painless and mobile nodule localized in the ventral part of the penis. The lesion was firstly evaluated through Doppler ultrasonography, which showed a hypoechoic and vascularized solid mass, a subsequent magnetic resonance confirmed size and position of the lesion. Subsequently the patient underwent a surgical excision of the mass, the pathological diagnosis was consistent with penile lymphoma, MALT-type. The patient underwent a consolidative immunotherapy with rituximab. Disease re-staging was performed through a MR without any detection of local or systemic recurrences.
Conclusion: To our knowledge, no cases of MALT lymphoma involving the penis have been reported in the literature so far. Surgical excision with organ sparing and immunotherapy with rituximab, successfully induced a complete response. Based upon this experience, we may recommend a conservative surgery associated with a systemic approach.
Keywords: MALT lymphoma; penile tumor.