Cu-catalyzed synthesis of tryptanthrin derivatives from substituted indoles

Chen Wang; Lianpeng Zhang; Anni Ren; Ping Lu; Yanguang Wang

doi:10.1021/ol401144m

Cu-catalyzed synthesis of tryptanthrin derivatives from substituted indoles

Org Lett. 2013 Jun 21;15(12):2982-5. doi: 10.1021/ol401144m. Epub 2013 Jun 7.

Authors

Chen Wang¹, Lianpeng Zhang, Anni Ren, Ping Lu, Yanguang Wang

Affiliation

¹ Department of Chemistry, Zhejiang University , Hangzhou 310027, P. R. China.

PMID: 23746360
DOI: 10.1021/ol401144m

Abstract

A concise method for the preparation of tryptanthrins from indoles via the copper-catalyzed aerobic oxidation is described. The reactions can be carried out under mild reaction conditions with varying functional group tolerance.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Catalysis
Copper / chemistry*
Indoles / chemistry*
Molecular Structure
Oxidation-Reduction
Quinazolines / chemical synthesis*
Quinazolines / chemistry

Substances

Indoles
Quinazolines
tryptanthrine
Copper